Rudger, ex-boyfriend of Jan's girlfriend Milene and biological father of their son, turns up at the practice of alternative practitioner Jan. He spent ten years in prison. Now he wants his wife and child back. It's clear to Jan that the man can't be helped with homeopathic doses. Heavy artillery must be brought to bear. Steve, a former colleague who has gone off the rails, promises to help. The operation goes wrong, Rudger rages and Jan flees to one of his patients. The terminally ill Dorothee has retreated to a mill - and has nothing to lose...

Emily (8) is terminally ill. Her parents ask the new CEO of a small pharmaceutical company, Dr. Julia Schemmel, for the early release of a drug that is not yet ready for the market. Dr. Julia Schemmel is to consolidate the company. The young company has to invest hundreds of millions of euros for each drug and is planning to go public. At the same time, Michael and Nicole Wagner receive the diagnosis that their daughter is suffering from incurable childhood dementia. During extensive internet research, Michael finds out that the pharmaceutical company "Berner & Braun" is researching a cure that has already been tested on people in Asia. It is said to slow down the progression of the disease, possibly even stop it. Together with other affected parents, the Wagners demand a study for children in Germany and the release of the drug.

Dedicated public prosecutor Judith Schrader is once again fighting organized crime in Berlin. This time she is investigating security companies that are increasingly in the hands of the OC.